Sitagliptin / Metformin 50 mg / 1000 mg Film-Coated Tablets
Why Sitagliptin / Metformin is used:
This medication contains two different medicines called Sitagliptin and Metformin.
- Sitagliptin belongs to a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors).
- Metformin belongs to a class of medicines called biguanides.
They work together to control blood sugar levels in adult patients with a type of diabetes called "Type 2 Diabetes Mellitus."
This medication helps increase insulin levels produced by the body after a meal and reduces the amount of sugar produced by your body.
Do not use Sitagliptin / Metformin:
- If you are allergic to Sitagliptin, Metformin, or any of the other ingredients of this medicine.
- If you have severely reduced kidney function.
- If you have uncontrolled diabetes, for example, severe hyperglycemia (high blood glucose), nausea, vomiting, diarrhea, rapid weight loss, lactic acidosis, or ketoacidosis.
- If you have a severe infection or are dehydrated.
- If you are going to have an X-ray where you will be injected with a dye. You will need to stop taking the medication at the time of the X-ray and for 2 or more days after, as directed by your doctor, depending on your kidney function.
- If you have recently had a heart attack or have severe circulatory problems, such as "shock" or breathing difficulties.
- If you have liver problems.
- If you drink alcohol excessively (either every day or only occasionally).
- If you are breastfeeding.
Warnings and Precautions:
- Cases of inflammation of the pancreas (pancreatitis) have been reported in patients receiving this medicine.
- If you experience skin blistering, it may be a sign of a condition called bullous pemphigoid. Your doctor may ask you to stop this medicine.
- Risk of lactic acidosis.
Talk to your doctor or pharmacist before taking if:
- You have or have ever had a disease of the pancreas (such as pancreatitis).
- You have gallstones, alcohol addiction, or very high levels of triglycerides (a type of fat) in your blood.
- You have Type 1 diabetes. This is sometimes called insulin-dependent diabetes.
- You have or have had an allergic reaction to Sitagliptin or Metformin.
- You are taking a sulfonylurea or insulin along with other diabetes medicines.
Possible Side Effects:
Stop using the product and seek immediate medical attention if you experience throat tightness, swelling of the eyes, face, lips, or tongue, feel faint, or have difficulty breathing.
Stop using the product if you develop hives or itching of the face or body.
Other Medicines and Sitagliptin / Metformin:
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. You may need more frequent blood glucose tests and kidney function checks, or your doctor may need to adjust the dose. It is especially important to mention:
- Medicines (taken orally, inhaled, or injected) used to treat inflammatory diseases, such as asthma and arthritis (corticosteroids).
- Medicines that increase urine production (diuretics).
- Medicines used to treat pain and inflammation (NSAIDs and COX-2 inhibitors, such as ibuprofen and celecoxib).
- Certain medicines for high blood pressure (ACE inhibitors and angiotensin II receptor antagonists).
- Specific medicines for bronchial asthma (β-sympathomimetics).
- Iodinated contrast agents or alcohol-containing medicines.
- Certain medicines used to treat stomach problems such as cimetidine.
- Ranolazine, a medicine used to treat angina.
- Dolutegravir, a medicine used to treat HIV infection.
- Vandetanib.
How to use Sitagliptin / Metformin:
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
- Take one tablet: twice daily by mouth.
- Take with meals to reduce the chance of an upset stomach.
- Your doctor may need to increase your dose to control your blood sugar.
- If you have reduced kidney function, your doctor may prescribe a lower dose.
How to store Sitagliptin / Metformin:
- Keep this medicine out of the sight and reach of children.
- Do not use this medicine after the expiry date which is stated on the blister and carton after "EXP".
- The expiry date refers to the last day of that month.
- Do not store above 30°C.
Product Details:
Quantity: 56 Tablets
Product Type: Tablets
Brand: Glipten
Concentration: 50/1000 mg
